Case Study

Fulfilling the Promise of Antibody-Drug Conjugates

Subject

Oncology

Capabilities

AnimationMusicScript WritingSound FXStoryboard

This case study details our direct partnership with Tubulis, a biotechnology company developing a new generation of highly stable antibody-drug conjugates (ADCs). Discover how we developed a unique visual approach to translate their proprietary linker chemistry into a clear and compelling animation, effectively demonstrating how its unique design overcomes key stability challenges inherent in conventional approaches.

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Watch the Animation

Fulfilling the Promise of ADC

PROJECT DELIVERABLES

  • 2-Minute MOA Animation: A full-length 3D animation showcasing the proprietary linker technology.
  • Script & Storyboard Development: Full co-development of the scientific narrative and visual plan in partnership with the client.
  • Styleframes: Establishing the distinct visual look and feel for the animation.
  • Music & Sound Design: A custom audio track to complement the scientific story.
  • Professional Voice-Over: Clear and precise narration for the animation.
  • Open Artwork Files: Providing source files for future localization and use.

PROJECT OVERVIEW

MadMicrobe partnered directly with Tubulis to create a sophisticated, two-minute animation showcasing their proprietary technology for ADC development. Our close partnership with the client involved co-developing the script and ensuring the accuracy of the scientific concepts illustrated. The objective was to create a powerful educational tool for investors, partners, and the scientific community that visually explains the chemical innovation behind the Tubulis linker. 

Styleframe of the ADC payload.

THE CHALLENGE

The central creative challenge was to visualize a highly technical and abstract concept: molecular stability. We needed to create a clear visual distinction between the client’s novel linker technology and conventional methods. The animation had to seamlessly transition between explaining the intricate chemistry of the linker and demonstrating its functional benefit within a biological context, all while maintaining the highest degree of scientific accuracy.

Fulfilling the Promise of Antibody-Drug Conjugates Oncology animation

THE SOLUTION: BLUEPRINT TO BIOLOGICAL ACTION

Our solution involved developing two distinct, complementary visual environments to tell the complete story. This dual-scene approach allowed us to address both the chemistry and the biology with precision and clarity.

First, we created a clean, technical “infographic engineering scene” that functioned like an interactive molecular software program. This environment allowed us to deconstruct the ADC, build the proprietary linker with its unique phosphorus core, and explain the chemistry with scientific authority.

Second, we used a dynamic “cellular environment” to demonstrate the technology in a biological context. Here, we established a powerful visual contrast: conventional ADCs were shown to be unstable, prematurely losing their toxic warheads. In contrast, the Tubulis ADC demonstrated its enhanced stability with a memorable and intuitive “snap back” animation, which clearly conveyed the strength of the bond.

Above: Storyboard frames to animated visualization.

IMPACT

The final animation provides Tubulis with a clear and sophisticated tool to explain their proprietary technology. The dual-scene narrative successfully bridges the gap between complex chemistry and tangible biological benefits, empowering the Tubulis team to effectively communicate their key differentiators. The animation serves as a critical asset for engaging with investors, potential partners, and the wider scientific community, clearly establishing the value of the Tubulis platform.

Cancer cell environment

Need to bring a complex mechanism or medical concept to life? MadMicrobe specializes in transforming your science into compelling visual narratives—on time, on brand, and with scientific integrity intact.

READY TO GET STARTED?
Reach out to Mike McIntyre at [email protected] (North America) or Vincent Elsey [email protected] (UK/EU) and let’s bring your science to life with clarity, beauty, and purpose.

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